HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

8-(4-Benzyloxy-phenyl)-6,7-dihydro-5H-1,4,8a-triaza-s-indacene → 4-(6,7-Dihydro-5H-1,4,8a-triaza-s-indacen-8-yl)-phenol

HRID 2251117
Notes
Print preview

Reaction equation

HRID 2251117 reaction equation
[N:1]1[N:9]2[C:4]([N:5]=[C:6]3[CH2:21][CH2:20][CH2:19]CC[C:7]3=[C:8]2[C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[CH:3][CH:2]=1.C(OC1C=CC(C2N3C(=CC=N3)N=C3C=2CCC3)=CC=1)C1C=CC=CC=1.[H][H]>[Pd]>[N:1]1[N:9]2[C:4]([N:5]=[C:6]3[C:7](=[C:8]2[C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH2:19][CH2:20][CH2:21]3)=[CH:3][CH:2]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

5

Reactant 3

HCID 692552828-(4-Benzyloxy-phenyl)-6,7-dihydro-5H-1,4,8a-triaza-s-indaceneHCID 1360572464-(6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]inden-10-yl)-phenolHCID 178418361HCID 178418361, compound

Product 1

HCID 1360572434-(6,7-Dihydro-5H-1,4,8a-triaza-s-indacen-8-yl)-phenol

Reagents, catalysts & solvents 1

HCID 23938
Palladium
Catalyst

Procedure

Using the method described for the preparation of 4-(6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]inden-10-yl)-phenol, the reaction of 8-(4-benzyloxy-phenyl)-6,7-dihydro-5H-1,4,8a-triaza-s-indacene and hydrogen in the presence of 10% Pd/C provided the title compound.

Sources & evidence

ORD record
ord-0fa1df9a69b74576be172fb69e213a4b
Source dataset
uspto-grants-2008_01
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US07319103B2

Reaction notes

Loading…

On this pageParticipantsProcedureSources & evidenceReaction notes