Borane → N-Benzyl-2-(3-bromobenzyl)-morpholine
Reaction equation
C(N1CCO[C@H](CC2C=CC=C(C=CC3C=NC=CC=3)C=2)C1)(OC(C)(C)C)=O.[CH2:29]([N:36]1[CH2:41][CH2:40][O:39][CH:38]([CH2:42][C:43]2[CH:48]=[CH:47][CH:46]=[C:45]([Br:49])[CH:44]=2)[C:37]1=O)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.B>>[CH2:29]([N:36]1[CH2:41][CH2:40][O:39][CH:38]([CH2:42][C:43]2[CH:48]=[CH:47][CH:46]=[C:45]([Br:49])[CH:44]=2)[CH2:37]1)[C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=1Participants
4
Procedure
N-Benzyl-2-(3-bromobenzyl)-morpholine was prepared as described for example 71, intermediate (a), but using N-benzyl-2-(3-bromobenzyl)-morpholin-3-one and borane and was isolated as a pale yellow oil.
Workup
- customwas isolated as a pale yellow oil