HCID 54338605, compound → 1-[2,4-Bis(methoxymethoxy)phenyl]-3-(4-methoxymethoxyphenyl)-1-propanone

HRID 2254262

Reaction equation

HRID 2254262 reaction equation
[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:24]=[C:23]([O:25][CH2:26][O:27][CH3:28])[CH:22]=[CH:21][C:6]=1[C:7](=[O:20])[CH:8]=[CH:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH2:17][O:18][CH3:19])=[CH:12][CH:11]=1>C(OCC)(=O)C.[Pd]>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:24]=[C:23]([O:25][CH2:26][O:27][CH3:28])[CH:22]=[CH:21][C:6]=1[C:7](=[O:20])[CH2:8][CH2:9][C:10]1[CH:11]=[CH:12][C:13]([O:16][CH2:17][O:18][CH3:19])=[CH:14][CH:15]=1

Participants

4

Reactant 1

HCID 54338605HCID 54338605, compound

Product 1

HCID 197448921-[2,4-Bis(methoxymethoxy)phenyl]-3-(4-methoxymethoxyphenyl)-1-propanone

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent2×

Procedure

Then, a suspension of 2.52 g of 5% palladium/carbon in 50 ml of ethyl acetate was hydrogenated for 2 hours, and a solution of 5.11 g of 2',4,4'-tris(methoxymethoxy)chalcone in 50 ml of ethyl acetate was added to the suspension and hydrogenation was carried out. After the reaction, the palladium/carbon was removed by filtration and the filtrate was concentrated under a reduced pressure to obtain 1-[2,4-bis(methoxymethoxy)phenyl]-3-(4-methoxymethoxyphenyl)-1-propanone.

Workup

  1. customAfter the reaction
  2. customthe palladium/carbon was removed by filtration
  3. concentrationthe filtrate was concentrated under a reduced pressure

Sources & evidence

ORD record
ord-83da20fced804de79fe55a8312907ea0
Source dataset
uspto-grants-1993_08
Patent number
US05234951

Linked notes

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