N-Phenylglycine → HCID 19100958, compound
Reaction equation
[CH2:1]([N:4]([CH2:10][CH:11]=O)[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3].[C:13]1([NH:19][CH2:20]C(O)=O)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1(C)C=CC=CC=1>[C:13]1([N:19]2[CH2:20][CH2:3][CH:2]3[CH:11]2[CH2:10][N:4]([C:5]([O:6][CH2:7][CH3:8])=[O:9])[CH2:1]3)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
8.6 g (50 mmol) of ethyl N-allyl-N-(2-oxoethyl)-carbamate and 7.6 g (50 mmol) of phenylglycine are heated under reflux overnight in 200 ml of toluene. The mixture is decanted from resinous material and concentrated, and the residue is distilled.
Workup
- customThe mixture is decanted from resinous material
- concentrationconcentrated
- distillationthe residue is distilled
Sources & evidence
- ORD record
- ord-79bf50925f8f4849b39e71b3ed55447c
- Source dataset
- uspto-grants-1993_08
- Patent number
- US05241076
Reaction notes
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