Water → HCID 54377907, compound

HRID 2256918

Reaction equation

HRID 2256918 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]([O:12][C:13]([F:16])([F:15])[F:14])[CH:8]=[CH:7][C:3]=1[C:4](F)=[O:5].[OH2:17]>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]([O:12][C:13]([F:16])([F:15])[F:14])[CH:8]=[CH:7][C:3]=1[C:4]([OH:17])=[O:5]

Participants

3

Reactant 2

HCID 962WaterHCID 539612062,3-Dichloro-4-trifluoromethoxybenzoyl fluoride

Product 1

HCID 54377907HCID 54377907, compound

Procedure

A suspension of crude 2,3-dichloro4-trifluoromethoxybenzoyl fluoride (2 g, containing mixed antimony halides) in water was stirred vigorously for 24 hours. The mixture was extracted with dichloromethane and filtered. The organic layer was washed with hydrochloric acid (2M), aqueous sodium chloride solution and extracted into sodium carbonate solution (2M). The aqueous extract was acidified to pH1 and the solid was filtered off and washed with water to give 2,3-dichloro-4-trifluoromethoxybenzoic acid (0.6 g) as a white solid mp 123°-126° C.

Workup

  1. extractionThe mixture was extracted with dichloromethane
  2. filtrationfiltered
  3. washThe organic layer was washed with hydrochloric acid (2M), aqueous sodium chloride solution
  4. extractionextracted into sodium carbonate solution (2M)
  5. extractionThe aqueous extract
  6. filtrationthe solid was filtered off
  7. washwashed with water

Sources & evidence

ORD record
ord-d3baf745aea248a3a776d22d9b203a3d
Source dataset
uspto-grants-1997_08
Patent number
US05656573

Linked notes

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