Propylene Glycol → L-lactide epsilon-caprolactone
Reaction equation
[CH2:1]([OH:5])[CH:2]([OH:4])[CH3:3]>C(O)(C(F)(F)F)C(F)(F)F>[C:1]1(=[O:5])[O:5][CH2:1][CH2:2][CH2:3][CH2:3][CH2:2]1.[CH3:3][C@@H:2]1[O:4][C:1](=[O:5])[C@H:2]([CH3:3])[O:4][C:1]1=[O:5]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The procedure in Example 3 was substantially repeated, except that 4.4 mL (60 mmol) propylene glycol (USP grade) was used instead of 5.6 mL of 1-dodecanol. The copolymer had an inherent viscosity of 0.17 dL/g in HFIP at 25° C.
Workup
- customat 25° C.
Sources & evidence
- ORD record
- ord-e82a49eb230f455cbaf06730dd7d2f50
- Source dataset
- uspto-grants-1998_03
- Patent number
- US05728752
Reaction notes
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