HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+)-Methyl 5-(3-(hydroxymethyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate → (+)-Methyl 5-(3-formylphenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+)-Methyl 5-(3-(hydroxymethyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate | HCID 19930508 | — |
| Catalyst | Manganese oxide | HCID 160959 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (+)-Methyl 5-(3-formylphenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate | HCID 19930537 | — |
Reaction Steps
To a solution of (+)-methyl 5-(3-(hydroxymethyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate (step 2) (679 mg) in ethyl acetate (30 mL) was added activated manganese oxide (1.3 g). The suspension was stirred overnight at room temperature. The suspension was filtered on a pad of silica gel and washed with EtOAc. The solvent was evaporated, affording the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05428171 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-85229504f92a4bcfb654f0b1fd1b508d |
| Source note | uspto-grants-1995_06 |