Water → HCID 178517449, compound
Reaction equation
O=[C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH2:3][S:4][C:5]#[N:6].O.S(=O)(=O)(O)[OH:15]>C(O)(=O)C>[C:7]1([C:2]2[N:6]=[C:5]([OH:15])[S:4][CH:3]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixed solution of 2-oxo-2-phenylethyl thiocyanate (5.67 g, 32.0 mmol), water (3.2 ml), concentrated sulfuric acid (0.832 ml) and acetic acid (26 ml) was stirred at 130° C. for 2 hours and at room temperature for 2 hours. A formed precipitate was collected by filtration and washed with water to give 4.78 g (84.3%) of the desired product.
Workup
- filtrationA formed precipitate was collected by filtration
- washwashed with water
Sources & evidence
- ORD record
- ord-c2c674fe9df84e358642efaac43b937c
- Source dataset
- uspto-grants-2010_12
- Patent number
- US07851473B2
Reaction notes
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