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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226892Generated: October 27, 2026

3-Chloro-4-methoxyaniline → N,N'-bis(3-chloro-4-methoxyphenyl)-5-fluoropyrimidine-2,4-diamine

https://huagongshe.com/reaction/226892

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-methoxyanilineHCID 21441—
Reactant2,4-Dichloro-5-fluoropyrimidineHCID 250705—
ProductN,N'-bis(3-chloro-4-methoxyphenyl)-5-fluoropyrimidine-2,4-diamineHCID 1266496—

Reaction Steps

In a like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 3-chloro-4-methoxyaniline were reacted to provide N2,N4-Bis(3-chloro-4-methoxyphenyl)-5-fluoro-2,4-pyrimidinediamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557210B2
Source datasetuspto-grants-2009_07
ORD IDord-49452b617dea4a4491a4cf5703bbac34
Source noteuspto-grants-2009_07