5-(2,2,2-Trifluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzaldehyde → 5-(1,2,2,2-Tetrafluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzaldehyde

Reaction equation

[F:1][C:2]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)([C:7]([F:10])([F:9])[F:8])[C:3]([F:6])([F:5])[F:4].FC(F)(F)C(C1C=CC(OC)=C(C=1)[CH:31]=[O:32])C(F)(F)F>>[F:1][C:2]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[C:13]([CH:12]=1)[CH:31]=[O:32])([C:7]([F:8])([F:9])[F:10])[C:3]([F:6])([F:5])[F:4]

Participants

Reactant 2

HCID 186776145-(2,2,2-Trifluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzaldehyde

HCID 186776424-(1,2,2,2-Tetrafluoro-1-(trifluoromethyl)ethyl)anisole

Product 1

HCID 186776235-(1,2,2,2-Tetrafluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzaldehyde

Procedure

This compound was prepared from Compound 16 in the same manner of Compound 9.

Sources & evidence

ORD record: ord-c17559c02db6426e857a1cd6af51d8be
Source dataset: uspto-grants-2001_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06329396B1

Reaction notes

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