(2S,3S)-tert-Butyl 3-amino-2-phenylpiperidine-1-carboxylate → (2s,3s)-1-Tert-butoxycarbonyl-3-(2,4-dimethoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine

Reaction equation

[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][N:4]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[C@H:3]1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[CH3:21][O:22][C:23]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([CH2:33][C:34]([F:37])([F:36])[F:35])=[CH:27][C:24]=1[CH:25]=O.C(OC(N1CCC[C@H](NCC2C=C(C(C(F)(F)F)C(F)(F)F)C=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:11]([O:10][C:8]([N:4]1[CH2:5][CH2:6][CH2:7][C@H:2]([NH:1][CH2:25][C:24]2[CH:27]=[C:28]([CH2:33][C:34]([F:35])([F:36])[F:37])[C:29]([O:31][CH3:32])=[CH:30][C:23]=2[O:22][CH3:21])[C@@H:3]1[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)=[O:9])([CH3:14])([CH3:13])[CH3:12]