Benzoxazole → 2-Methyl-5-(oxiran-2-ylmethoxy)benzothiazole
Reaction equation
[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][C:5]=2[N:6]=1.[O:12]1[C:16]2[CH:17]=[CH:18]C=CC=2N=C1>>[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][C:8]([O:11][CH2:18][CH:17]3[CH2:16][O:12]3)=[CH:7][C:5]=2[N:6]=1Participants
3
Procedure
Compound 33 was prepared in the manner of compound 6 substituting 2-methyl- benzothiazol-5-ol for compound 8 in partC-5 of Example 1.
Sources & evidence
- ORD record
- ord-da2ee1e1488f40f4a37ec38a09cc0de4
- Source dataset
- uspto-grants-2005_02
- Patent number
- US06849632B2
Reaction notes
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