Benzoxazole → 2-Methyl-6-(oxiran-2-ylmethoxy)benzothiazole

HRID 22706Notes

Reaction equation

[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:5]=2[N:6]=1.[O:12]1[C:16]2[CH:17]=[CH:18]C=CC=2N=C1>>[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][CH2:18][CH:17]3[CH2:16][O:12]3)[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

Reactant 2

HCID 9228Benzoxazole

HCID 7593042-Methyl-1,3-benzothiazol-6-ol

Product 1

HCID 225916342-Methyl-6-(oxiran-2-ylmethoxy)benzothiazole

Procedure

Compound 51 was prepared in the manner of compound 6 substituting compound 50 for compound 8 in part C-5 of Example 1.

Sources & evidence

ORD record: ord-99297eb265244011880deeebc439d674
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06849632B2

Reaction notes

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