Sodium Carbonate → 5-(Bromomethyl)-3-(3-(difluoromethoxy)phenyl)-2-ethoxypyrazine
Reaction equation
[F:1][CH:2]([F:20])[O:3][C:4]1[CH:5]=[C:6]([C:10]2[C:11]([O:17][CH2:18][CH3:19])=[N:12][CH:13]=[C:14]([CH3:16])[N:15]=2)[CH:7]=[CH:8][CH:9]=1.[Br:21]C1C(OCC)=NC=C(C)N=1.B(O)O.C(=O)([O-])[O-].[Na+].[Na+]>CCO.C1(C)C=CC=CC=1.[Pd].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>[Br:21][CH2:16][C:14]1[N:15]=[C:10]([C:6]2[CH:7]=[CH:8][CH:9]=[C:4]([O:3][CH:2]([F:1])[F:20])[CH:5]=2)[C:11]([O:17][CH2:18][CH3:19])=[N:12][CH:13]=1Participants
8
