HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Methanesulfonic acid 2-(1-methyl-pyrrolidin-2-yl)-ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 1-Methyl-2-pyrrolidineethanol | HCID 93363 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Methanesulfonic acid 2-(1-methyl-pyrrolidin-2-yl)-ethyl ester | HCID 44627019 | — |
Reaction Steps
The 1-methyl-2-pyrrolidineethanol (Aldrich, 0.16 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560481B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-0dbdb683028e47d7a0c4b45b508af8c3 |
| Source note | uspto-grants-2009_07 |