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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2275111Generated: October 25, 2026

4-(1-Pyrrolidinyl)piperidine → 6,6-Dimethyl-11-oxo-8-(4-pyrrolidin-1-yl-piperidin-1-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/reaction/2275111

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-Pyrrolidinyl)piperidineHCID 78703—
ReactantTrifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl esterHCID 86663817—
Product6,6-Dimethyl-11-oxo-8-(4-pyrrolidin-1-yl-piperidin-1-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 49804866—

Reaction Steps

Under the same conditions as the method for synthesizing Compound B2-1, the title compound was prepared from Compound B1 and 4-pyrrolidin-1-yl-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09126931B2
Source datasetuspto-grants-2015_09
ORD IDord-a20a30a37b5c44c9a8e034e98f7e2600
Source noteuspto-grants-2015_09