Phenyl isocyanate → 1-Phenylaminocarbonyl-1,3-dicyclohexyl-O-(N-2-butylideneamino)-isourea

HRID 2275478

Reaction equation

HRID 2275478 reaction equation
[CH:1]1([NH:7][C:8](=[N:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[O:9][N:10]=[C:11]([CH2:13][CH3:14])[CH3:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:22]1([N:28]=[C:29]=[O:30])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>ClCCl>[C:22]1([NH:28][C:29]([N:15]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[C:8](=[N:7][CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[O:9][N:10]=[C:11]([CH2:13][CH3:14])[CH3:12])=[O:30])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 866646331,3-Dicyclohexyl-O-(N-2-butylideneamino)-isourea

Product 1

HCID 866646411-Phenylaminocarbonyl-1,3-dicyclohexyl-O-(N-2-butylideneamino)-isoureaYield 99.9%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 1,3-dicyclohexyl-O—(N-2-butylideneamino)-isourea (Cmpd. 2) (2.93 g, 10 mmol) in dichloromethane (15 ml) is phenylisocyanate (1.19 g, 10 mmol). The mixture is stirred 1 h at room temperature and evaporated to afford 4.12 g of the title compound as a light yellow oil.

Workup

  1. customevaporated

Sources & evidence

ORD record
ord-31a0477833de44acaafe934fc805a700
Source dataset
uspto-grants-2015_09
Patent number
US09127098B2

Linked notes

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