(2-Butoxy-4-fluorophenyl)boronic acid → HCID 90407314, compound
Reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[CH2:16]([O:20][C:21]1[CH:26]=[C:25]([F:27])[CH:24]=[CH:23][C:22]=1B(O)O)[CH2:17][CH2:18][CH3:19]>>[CH2:16]([O:20][C:21]1[CH:26]=[C:25]([F:27])[CH:24]=[CH:23][C:22]=1[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1)[CH2:17][CH2:18][CH3:19]Participants
3
Procedure
The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile (PREPARATION 2) and 2-butoxy-4-fluorophenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H19FN4O, 351. Found, 351.
Sources & evidence
- ORD record
- ord-1ecea69443324f0aa6330e0c73d62ed9
- Source dataset
- uspto-grants-2015_09