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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 22792Generated: October 25, 2026

1,1,3,3-Tetramethylbutyl isocyanide → [6,8-Dibromo-2-(2,3-dimethoxyphenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethylbutyl)-amine

https://huagongshe.com/reaction/22792

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,3,3-Tetramethylbutyl isocyanideHCID 26725—
Reactant2,3-DimethoxybenzaldehydeHCID 66581—
ReactantWisteria sinensis, ext.HCID 522994—
SolventPerchloric AcidHCID 24247—
Product[6,8-Dibromo-2-(2,3-dimethoxyphenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethylbutyl)-amineHCID 9829072—

Reaction Steps

Compound (6) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-3,5-dibromo-6-methylpyridine solution (0.1 M, DCM), 0.575 ml of 1,1,3,3-tetramethylbutyl isocyanide solution (0.2 M, DCM), 0.500 ml of 2,3-dimethoxybenzaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06849642B2
Source datasetuspto-grants-2005_02
ORD IDord-2162421c093a43f59d81760000eb9656
Source noteuspto-grants-2005_02