HuagongsheHuagongshe Chemistry Print Report · For research reference only
Perchloric Acid → (8-Benzyloxy-2-cyclohexylimidazo[1,2-a]pyridin-3-ylamino)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Perchloric Acid | HCID 24247 | — |
| Reactant | 2-Amino-3-benzyloxypyridine | HCID 90334 | — |
| Reactant | Methyl isocyanoacetate | HCID 547815 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (8-Benzyloxy-2-cyclohexylimidazo[1,2-a]pyridin-3-ylamino)-acetic acid methyl ester | HCID 69732054 | — |
Reaction Steps
Compound (30) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-3-benzyloxypyridine solution (0.1 M, DCM), 0.575 ml of methyl isocyanoacetate solution (0.2 M, DCM), 0.500 ml of cyclohexylcarbaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849642B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-f5bdd3d63b7542b3a523339961db6ca0 |
| Source note | uspto-grants-2005_02 |