1H-Benzimidazol-6-amine, 2-(4-aminophenyl)- → HCID 178521897, compound

Reaction equation

[NH2:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([NH2:15])=[CH:11][CH:10]=3)[NH:8][C:4]=2[CH:3]=1.[C:18]1([C:24]([OH:26])=O)[CH2:23][CH2:22][CH2:21][CH2:20]C=1>>[C:18]1([C:24]([NH:1][C:2]2[CH:17]=[CH:16][C:5]3[NH:6][C:7]([C:9]4[CH:10]=[CH:11][C:12]([NH:15][C:24]([C:18]5[CH2:23][CH2:22][CH2:21][CH:20]=5)=[O:26])=[CH:13][CH:14]=4)=[N:8][C:4]=3[CH:3]=2)=[O:26])[CH2:20][CH2:21][CH2:22][CH:23]=1

Participants

Reactant 2

HCID 242601H-Benzimidazol-6-amine, 2-(4-aminophenyl)-

HCID 694701-Cyclohexene-1-carboxylic acid

Product 1

HCID 178521897HCID 178521897, compound

Procedure

Compound 182 was prepared according to the procedure similar to that described in Scheme III from 5-amino-2-(4-aminophenyl)benzimidazole and 1-cyclohexenecarboxylic acid. [M+H]+ calcd for C25H24N4O2: 413.20; found: 412.96.

Sources & evidence

ORD record: ord-c47a63ebc0354b1aab2fa3838ca37cd7
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09144557B2

Reaction notes

Loading…