HCID 56988678, compound → 2-Propylhydroquinone
Reaction equation
[CH:1]([C:4]1[CH:9]=[C:8]([O:10]CC2C=CC=CC=2)[CH:7]=[CH:6][C:5]=1[OH:18])=[CH:2][CH3:3]>CO.[Pd]>[CH2:1]([C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:18])[CH2:2][CH3:3]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
6.8 grams (28.4 mmole, 1.0 eq.) of product from step B was dissolved in 60 ml of methanol. 680 mg of 10% palladium on carbon (0.64 mmole, 0.023 eq.) was added and the stirring suspension was evacuated and charged with hydrogen. After 16 hours the catalyst was filtered over celite and the filtrate evaporated. The title compound (4.3 grams) was recovered by recrystallization from dichloromethane/hexanes.
Workup
- customthe stirring suspension was evacuated
- additioncharged with hydrogen
- filtrationAfter 16 hours the catalyst was filtered over celite
- customthe filtrate evaporated
- customThe title compound (4.3 grams) was recovered by recrystallization from dichloromethane/hexanes
Sources & evidence
- ORD record
- ord-4b2b796d0d754fdfac270763a8bb5c87
- Source dataset
- uspto-grants-2000_07
- Patent number
- US06090836
Reaction notes
Loading…