HuagongsheHuagongshe Chemistry Print Report · For research reference only
Itaconic acid → 5-Oxo-1-(3-{(benzylamino)carbonylamino}-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Itaconic acid | HCID 811 | — |
| Reactant | n-(3-Amino-5-(trifluoromethyl)phenyl)(benzylamino)carboxamide | HCID 22591859 | — |
| Product | 5-Oxo-1-(3-{(benzylamino)carbonylamino}-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid | HCID 22591872 | — |
Reaction Steps
A mixture of N-(3-amino-5-(trifluoromethyl)phenyl)(benzylamino)carboxamide and itaconic acid was fused at 110° C. for 10 hours. The resulted solid was washed with methanol and then dried at 50° C. for 12 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849639B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-864cef6e6f664a059be8b4a512c33fb1 |
| Source note | uspto-grants-2005_02 |