Diketene → 2-Methoxy-2-phenylethyl acetoacetate

HRID 2290832Notes

Reaction equation

HRID 2290832 reaction equation
[CH2:1]=[C:2]1[O:6][C:4](=[O:5])[CH2:3]1.[CH3:7][O:8][CH:9]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:10][OH:11]>>[C:4]([O:11][CH2:10][CH:9]([O:8][CH3:7])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=[O:5])[CH2:3][C:2]([CH3:1])=[O:6]

Participants

3

Reactant 2

HCID 12661DiketeneHCID 102910Benzeneethanol, beta-methoxy-

Product 1

HCID 136697232-Methoxy-2-phenylethyl acetoacetate

Procedure

In a similar manner, diketene was reacted with (±)-2-methoxy-2-phenylethanol to obtain 2-methoxy-2-phenylethyl acetoacetate, BP 115°-120° C./0.2 mm.

Sources & evidence

ORD record
ord-6a60c24597b64ccab91adee7f8f82d22
Source dataset
uspto-grants-1986_10
Patent number
US04618678

Reaction notes

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