1,10-Undecanediol → 4-(Hydroxymethyl)cyclohexan-1-one
Reaction equation
C(O)CCCCCCCCC(O)C.[OH:14][CH2:15][CH:16]1[CH2:21][CH2:20][CH:19]([OH:22])[CH2:18][CH2:17]1>C(O)(=O)C>[OH:14][CH2:15][CH:16]1[CH2:21][CH2:20][C:19](=[O:22])[CH2:18][CH2:17]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 55 °C
Procedure
To acetic acid in which Ce (IV)/PFCP (50 mg, 0.027 mmole) and 200 mg of NaBrO3 were dispersed and dissolved, 1.0 mmole of 1,10-undecane diol and 1.0 mmole of 4-hydroxymethyl cyclohexanol were added, respectively. The reaction mixture was heated for three hours at 55° C. and the product was purified with a column chromatography to yield 154 mg (82% yield) of 10-undecane-1-ol and 93 mg (73% yield) of 4-hydroxymethyl cyclohexanone.
Workup
- dissolutiondissolved
- customthe product was purified with a column chromatography
Sources & evidence
- ORD record
- ord-f5c3815be4c94793a69f03df51be1fd2
- Source dataset
- uspto-grants-1986_10
- Patent number
- US04618724
Reaction notes
Loading…