BW-4030W92, (-)- → BW-202W92

Reaction equation

[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH2:17][F:18])[N:3]=1.NC1N=C(N)C(C2C=C([Cl:33])C=C(Cl)C=2Cl)=C(CO)N=1>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([Cl:33])[CH:12]=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH2:17][F:18])[N:3]=1

Participants

Reactant 2

HCID 9860692BW-4030W92, (-)-

HCID 197050632,4-Diamino-5-(2,3,5-trichlorophenyl)-6-hydroxymethylpyrimidine

Product 1

HCID 9883607BW-202W92

Procedure

This compound was prepared in an analogous manner to the compound of Example 18 from 2,4-diamino-5-(2,3,5-trichlorophenyl)-6-hydroxymethylpyrimidine, mp. 215°-217° C.

Sources & evidence

ORD record: ord-24deaa394dc4492cbe714d712a205df4
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05684005

Reaction notes

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