Potassium Hydroxide → 2-Imino-1,3-dimethylimidazolidin-4-one

HRID 2293031

Reaction equation

HRID 2293031 reaction equation
[OH-].[K+].I.[NH:4]=[C:5]1[N:9]([CH3:10])[C:8](=[O:11])[CH2:7][N:6]1[CH3:12]>CO>[NH:4]=[C:5]1[N:9]([CH3:10])[C:8](=[O:11])[CH2:7][N:6]1[CH3:12]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 214757732-Imino-1,3-dimethylimidazolidin-4-one hydroiodide

Product 1

HCID 140604272-Imino-1,3-dimethylimidazolidin-4-oneYield 90.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Then, to 150 ml of a methanol solution containing 5.17 g (78.4 mmol) of 85% potassium hydroxide, 20 g (78.4 mmol) of 2-imino-1,3-dimethylimidazolidin-4-one hydroiodide was added, and the mixture was stirred at room temperature for 20 minutes. The solvent was distilled off under reduced pressure. Then, to the residue, 200 ml of chloroform was added, and insoluble matters were filtered off. The filtrate was dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure to obtain 9.0 g of 2-imino-1,3-dimethylimidazolidin-4-one.

Workup

  1. additionwas added
  2. distillationThe solvent was distilled off under reduced pressure
  3. additionThen, to the residue, 200 ml of chloroform was added
  4. filtrationinsoluble matters were filtered off
  5. dry with materialThe filtrate was dried over anhydrous magnesium sulfate
  6. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-45fefeba9e9e4219a4c24dc7727bc4c4
Source dataset
uspto-grants-1997_11
Patent number
US05686390

Linked notes

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