Cuminol → 4-Isopropylbenzyl 5-aminolevulinate hydrochloride

HRID 229483

Reaction equation

HRID 229483 reaction equation
[CH:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8][OH:9])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[ClH:12].[NH2:13][CH2:14][C:15](=[O:21])[CH2:16][CH2:17][C:18](O)=[O:19]>>[ClH:12].[NH2:13][CH2:14][C:15](=[O:21])[CH2:16][CH2:17][C:18]([O:9][CH2:8][C:7]1[CH:6]=[CH:5][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:11][CH:10]=1)=[O:19]

Participants

3

Reactant 2

HCID 325CuminolHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 222531474-Isopropylbenzyl 5-aminolevulinate hydrochloride

Procedure

From 4-isopropylbenzyl alcohol (5.0 ml) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol). The reaction was complete after 2 days. The yield was 1.0 g (56%).

Sources & evidence

ORD record
ord-d6291a4f4ce6459686567d31cecd90a2
Source dataset
uspto-grants-2009_07
Patent number
US07563819B1

Linked notes

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