2-Ethylcyclohexan-1-amine → 2-Ethylaniline

HRID 2296506Notes

Reaction equation

HRID 2296506 reaction equation
[O-2].[Ca+2].[O-2].[Al+3].[O-2].[O-2].[Al+3].[CH2:8]([CH:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH:11]1[NH2:16])[CH3:9]>[Pd]>[CH2:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[NH2:16])[CH3:9]

Participants

5

Reactant 3

HCID 5448542-Ethylcyclohexan-1-amineHCID 6850728CalciumoxideHCID 9989226Alumina

Product 1

HCID 113572-EthylanilineYield 95%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The procedure described in Example 27 is followed, using a reaction temperature of 250° C. and a catalyst which contains 0.5% by weight of palladium on a mixture of 19.4% by weight of calcium oxide and 80.6% by weight of aluminum oxide, and starting from 2-ethylcyclohexylamine. o-Ethylaniline (boiling point=210° C.) is obtained in a yield of 95% of the theory.

Workup

  1. customa reaction temperature of 250° C.

Sources & evidence

ORD record
ord-7047ce36165548e0b0dda930a92fa923
Source dataset
uspto-grants-1984_01
Patent number
US04429155

Reaction notes

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