Reaction equation
[CH2:1]=[CH:2][C:3]1C=CC=CC=1.CC(C(O[CH2:15][CH2:16][O:17][C:18]([C:20]([CH3:22])=[CH2:21])=[O:19])=O)=C.[CH3:23][CH2:24]C(N=NC(C#N)(CC)C)(C#N)C.[CH:37]1(O)CCCC[CH2:38]1.[CH2:44]([OH:56])[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH3:55]>O>[CH3:37][C@@:38]12[C@@H:44]([OH:56])[CH2:45][CH2:46][C@H:47]1[C@H:48]1[C@@H:53]([C:52]3[CH:23]=[CH:24][C:16]([O:17][C:18]([C:20]4[CH:21]=[CH:1][CH:2]=[CH:3][CH:22]=4)=[O:19])=[CH:15][C:51]=3[CH2:50][CH2:49]1)[CH2:54][CH2:55]2Participants
7
Reactant 5
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 90 °C
Procedure
To a 500 mL glass resin keftle (equipped with water-driven condenser, air-driven agitator with Teflon® paddle, N2 sweep, and heating mantle) 100 mL water with 1.2 g polyvinylpyrolidone was charged. This suspending medium was heated to approximately 90° C. and agitation of 700 rpm was then achieved. A pre-heated glass syringe was used to dropwise add a previously mixed reaction mixture of 0.82 g MAA, 0.99 g styrene, 18.2 g EGDMA, 1.78 g EB, 0.16 g VAZO-67®, 18.71 g cyclohexanol, and 1.96 g dodecylalcohol to the water by gravity feed. Dropwise addition of the monomer-template reaction mixture was complete in 35 min. Polymerization was complete 20 min thereafter, and the polymer beads were recovered via Buchner filtration.
Workup
- customA pre-heated glass syringe was used
- additionto dropwise add
- additionDropwise addition of the monomer-template reaction mixture
- customPolymerization
- waitwas complete 20 min
- filtrationthe polymer beads were recovered via Buchner filtration
Sources & evidence
- ORD record
- ord-cd593ef36b234da0a3c9dcdbaf4a3517
- Source dataset
- uspto-grants-2005_02
- Patent number
- US06849701B2
Linked notes
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