L-Alanine → N-(Phenylacetyl)-L-alanine

Reaction equation

[C:1]1([CH2:7][C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:11][C@H:12]([C:14]([OH:16])=[O:15])[CH3:13]>>[C:1]1([CH2:7][C:8]([NH:11][C@H:12]([C:14]([OH:16])=[O:15])[CH3:13])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 5950L-Alanine

HCID 7679Phenylacetyl chloride

Product 1

HCID 7004640N-(Phenylacetyl)-L-alanine

Procedure

Using General Procedure II-C, the title compound was prepared from phenylacetyl chloride (Aldrich) and L-alanine (Aldrich) as a solid having a melting point of 102-104° C.

Sources & evidence

ORD record: ord-8f16b871cff54491b9aa2724ccaea054
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06849650B2

Reaction notes

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