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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 23010Generated: October 23, 2026

Cyclopropaneacetic acid → N-(Cyclopropylacetyl)-L-alanine

https://huagongshe.com/en/reaction/23010

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropaneacetic acidHCID 138440—
ReactantAlanine methyl ester hydrochlorideHCID 2733257—
ProductN-(Cyclopropylacetyl)-L-alanineHCID 54556694—

Reaction Steps

Following General Procedure II-E above using cyclopropylacetic acid (Aldrich) and L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification was by flash column chromatography using 25% ethyl acetate/hexanes as the eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06849650B2
Source datasetuspto-grants-2005_02
ORD IDord-c1aa1f135199484289799d0967d68dae
Source noteuspto-grants-2005_02