2-Thiopheneglyoxylic acid → 7-methoxy-3-thiophen-2-yl-1H-quinoxalin-2-one

HRID 230218

Reaction equation

HRID 230218 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:10])[C:6]([NH2:9])=[CH:7][CH:8]=1.[S:11]1[CH:15]=[CH:14][CH:13]=[C:12]1[C:16](=O)[C:17](O)=[O:18]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:6]([N:9]=[C:16]([C:12]3[S:11][CH:15]=[CH:14][CH:13]=3)[C:17](=[O:18])[NH:10]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 776942-Thiopheneglyoxylic acidHCID 1534044-Methoxy-o-phenylenediamine

Product 1

HCID 210836747-methoxy-3-thiophen-2-yl-1H-quinoxalin-2-one

Procedure

The quinoxalin-2-one of the present example is prepared with 4-Methoxy-benzene-1,2-diamine and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 7-Methoxy-3-thiophen-2-yl-1H-quinoxalin-2-one.

Sources & evidence

ORD record
ord-1a3051a0493f40648eef1611de919aa1
Source dataset
uspto-grants-2009_07
Patent number
US07566719B2

Linked notes

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