3-(3-Chlorophenoxy)propylamine → HCID 178479732, compound

Reaction equation

[N:1]1[C:5]2[CH2:6][CH2:7][CH:8]([C:10]([OH:12])=O)[CH2:9][C:4]=2[NH:3][CH:2]=1.[Cl:13][C:14]1[CH:15]=[C:16]([CH:22]=[CH:23][CH:24]=1)[O:17][CH2:18][CH2:19][CH2:20][NH2:21]>>[ClH:13].[Cl:13][C:14]1[CH:15]=[C:16]([CH:22]=[CH:23][CH:24]=1)[O:17][CH2:18][CH2:19][CH2:20][NH:21][C:10]([CH:8]1[CH2:7][CH2:6][C:5]2[NH:1][CH:2]=[N:3][C:4]=2[CH2:9]1)=[O:12]

Participants

Reactant 2

HCID 104650253-(3-Chlorophenoxy)propylamine

HCID 110301834,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic acid

Product 1

HCID 178479732HCID 178479732, compound

Procedure

By a similar procedure as described in Example 65, the title compound was prepared from 4,5,6,7-tetrahydrobenzimidazole-5-carboxylic acid and 3-(3-chlorophenoxy)propylamine.

Sources & evidence

ORD record: ord-b69d8d20203546f2b48f8df3fb4ec3fb
Source dataset: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06437147B1

Reaction notes

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