4-Chloroquinoline → 4-Chloro-2-(2,3-dihydro-benzofuran-5-yl)-quinoline

HRID 2305557

Reaction equation

HRID 2305557 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.I[C:13]1[CH:14]=[CH:15][C:16]2[O:20][CH2:19][CH2:18][C:17]=2[CH:21]=1>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:13]2[CH:14]=[CH:15][C:16]3[O:20][CH2:19][CH2:18][C:17]=3[CH:21]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 691404-ChloroquinolineHCID 27361335-Iodo-2,3-dihydro-1-benzofuran

Product 1

HCID 184330254-Chloro-2-(2,3-dihydro-benzofuran-5-yl)-quinoline

Procedure

The title compound, m. p. 130-132° C., MS: m/e=281 (M+), was prepared from 4-chloro-quinoline and 5-iodo-2,3-dihydrobenzofuran.

Sources & evidence

ORD record
ord-489c03cb8f794f5181898ce2c7ab0027
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Linked notes

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