4-Chloroquinoline → 4-Chloro-2-chroman-6-yl-quinoline
Reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.Br[C:13]1[CH:14]=[C:15]2[C:20](=[CH:21][CH:22]=1)[O:19][CH2:18][CH2:17][CH2:16]2>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:13]2[CH:14]=[C:15]3[C:20](=[CH:21][CH:22]=2)[O:19][CH2:18][CH2:17][CH2:16]3)[CH:3]=1Participants
3
Procedure
The title compound, MS: m/e=295 (M+), was prepared from 4-chloro-quinoline and 6-bromo-chroman.
Sources & evidence
- ORD record
- ord-9f8adb1827a741c4afaca77d5081e556
- Source dataset
- uspto-grants-2002_08
- Patent number
- US06440995B1
Reaction notes
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