HCID 18433365, compound → HCID 9933248, compound

Reaction equation

C[O:2][C:3](=[O:15])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:13]=[C:12]([NH2:14])[CH:11]=[CH:10][CH:9]=1.[N:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH:22][C:23]2[O:24][C:25]3[CH:31]=[C:30]([CH2:32][C:33](O)=[O:34])[CH:29]=[CH:28][C:26]=3[N:27]=2)[CH:17]=1>>[N:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH:22][C:23]2[O:24][C:25]3[CH:31]=[C:30]([CH2:32][C:33]([NH:14][C:12]4[CH:11]=[CH:10][CH:9]=[C:8]([O:7][CH2:6][CH2:5][CH2:4][C:3]([OH:2])=[O:15])[CH:13]=4)=[O:34])[CH:29]=[CH:28][C:26]=3[N:27]=2)[CH:17]=1

Participants

Reactant 2

HCID 18433365HCID 18433365, compound

HCID 18433369HCID 18433369, compound

Product 1

HCID 9933248HCID 9933248, compound

Procedure

Methyl4-(5-aminophenoxy)butyrate was made as described in example 7 above and coupled with 2-(3-pyridylamino)-6-carboxymethylbenzoxazole according to the method described in example 7 to produce the methyl ester of 2-(3-pyridylamino)-6-{3-[3-carboxypropoxy]anilinocarbonyl methyl}benzoxazole

Sources & evidence

ORD record: ord-67ef432eb92f406b8c735b6e8fef7f08
Source dataset: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06441012B1

Reaction notes

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