Cyclohexylhydroxylamine → alpha-(2,4,6-Triethoxyphenyl)-N-cyclohexylnitrone
Reaction equation
[CH2:1]([O:3][C:4]1[CH:11]=[C:10]([O:12][CH2:13][CH3:14])[CH:9]=[C:8]([O:15][CH2:16][CH3:17])[C:5]=1[CH:6]=O)[CH3:2].[CH:18]1([NH:24][OH:25])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH2:1]([O:3][C:4]1[CH:11]=[C:10]([O:12][CH2:13][CH3:14])[CH:9]=[C:8]([O:15][CH2:16][CH3:17])[C:5]=1[CH:6]=[N+:24]([CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1)[O-:25])[CH3:2]Participants
3
Procedure
The title compound was prepared according to the procedure described in Example 11 using 2,4,6-triethoxybenzaldehyde and N-cyclohexylhydroxylamine. The title compound was isolated in 87.4% yield as a solid, m.p. 145.7° C.
Workup
- customThe title compound was prepared
Sources & evidence
- ORD record
- ord-740c167b74f64d018b80d1188b563e03
- Source dataset
- uspto-grants-2002_08