Acetyl chloride → 1-Acetyl-2-(4-bromophenyl)pyrrolidine
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[C:13](Cl)(=[O:15])[CH3:14]>>[C:13]([N:9]1[CH2:10][CH2:11][CH2:12][CH:8]1[C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=1)(=[O:15])[CH3:14]Participants
3
Procedure
The title compound was prepared from 2-(4-bromophenyl)pyrrolidine and acetyl chloride using a similar procedure to that described in description 25.
Sources & evidence
- ORD record
- ord-ed14abbda5904a78bfa0dafec6a5f394
- Source dataset
- uspto-grants-2009_07
- Patent number
- US07566735B2
Reaction notes
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