1-(4-Iodophenyl)ethan-1-one → 1-{4-[3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazol-1-yl]phenyl}ethanone

HRID 230656

Reaction equation

HRID 230656 reaction equation
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7](I)=[CH:6][CH:5]=1)=[O:3].[F:11][C:12]([F:23])([F:22])[C:13]1[C:21]2[CH2:20][CH2:19][CH2:18][CH2:17][C:16]=2[NH:15][N:14]=1>>[F:23][C:12]([F:11])([F:22])[C:13]1[C:21]2[CH2:20][CH2:19][CH2:18][CH2:17][C:16]=2[N:15]([C:7]2[CH:8]=[CH:9][C:4]([C:2](=[O:3])[CH3:1])=[CH:5][CH:6]=2)[N:14]=1

Participants

3

Reactant 2

HCID 728691-(4-Iodophenyl)ethan-1-oneHCID 28028633-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole

Product 1

HCID 248269471-{4-[3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazol-1-yl]phenyl}ethanone

Procedure

The title compound was prepared from 4-iodoacetophenone and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 7.

Sources & evidence

ORD record
ord-a6fb2d367f764cd69a0920175190285d
Source dataset
uspto-grants-2009_07
Patent number
US07566735B2

Linked notes

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