4-Chloro-3-nitrobenzaldehyde → HCID 69721144, compound

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[C@@H:13]1([NH2:23])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH:23][C@@H:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:16][CH2:15][CH2:14]2)=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11]

Participants

Reactant 2

HCID 855054-Chloro-3-nitrobenzaldehyde

HCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69721144HCID 69721144, compound

Procedure

4-Chloro-3-nitrobenzaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record: ord-89bd187bff0e45a997a7649979f16808
Source dataset: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06831193B2

Reaction notes

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