3-(Allyloxy)benzaldehyde → HCID 69720772, compound

Reaction equation

[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[CH:8]=O)[CH:2]=[CH2:3].[C@@H:13]1([NH2:23])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1>>[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[CH2:8][NH:23][C@@H:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1)[CH:2]=[CH2:3]

Participants

Reactant 2

HCID 27166123-(Allyloxy)benzaldehyde

HCID 70580741-Aminotetralin, (S)-

Product 1

HCID 69720772HCID 69720772, compound

Procedure

The product from Example 58A and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record: ord-6cd6420b17444cf1a677a4ccf8c19d41
Source dataset: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06831193B2

Reaction notes

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