Methyl 2-(4-(2-oxopropyl)phenoxy)acetate → HCID 20186769, compound

Reaction equation

[C:1]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14](=O)[CH3:15])=[CH:9][CH:8]=1)([O:3][CH3:4])=[O:2].[CH2:17]([O:24][C:25]1[CH:30]=[CH:29][C:28]([CH:31]([O:34][CH2:35][CH2:36][OH:37])[CH2:32][NH2:33])=[CH:27][CH:26]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:1]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH:14]([NH:33][CH2:32][CH:31]([C:28]2[CH:29]=[CH:30][C:25]([O:24][CH2:17][C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:26][CH:27]=2)[O:34][CH2:35][CH2:36][OH:37])[CH3:15])=[CH:9][CH:8]=1)([O:3][CH3:4])=[O:2]

Participants

Reactant 2

HCID 13851156Methyl 2-(4-(2-oxopropyl)phenoxy)acetate

HCID 20186765HCID 20186765, compound

Product 1

HCID 20186769HCID 20186769, compound

Procedure

The title compound was prepared as an oil from 1-(4-carbomethoxymethoxyphenyl)propan-2-one (4.52 g) and 2-(4-benzyloxyphenyl)-2-(2-hydroxyethoxy)ethanamine (5.84 g) as described in Example 1.

Sources & evidence

ORD record: ord-eedecc5914614f4bbe8510e7f06bf772
Source dataset: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04692465

Reaction notes

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