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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 23094Generated: October 27, 2026

Phenylacetic Acid → 2-(phenylacetamido)butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/23094

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetic AcidHCID 999—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-(phenylacetamido)butyric Acid Iso-butyl EsterHCID 54176777—

Reaction Steps

Following General Procedure BH above and using phenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above) the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by chromatography on silica gel using 9:1 toluene: EtOAc as the eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06849650B2
Source datasetuspto-grants-2005_02
ORD IDord-01993111ebdf4eef835a7c3166fdf998
Source noteuspto-grants-2005_02