2,5-diketo-D-gluconic acid → 2-keto-D-Gluconic acid

HRID 2309676Notes

Reaction equation

HRID 2309676 reaction equation
[CH2:1]([OH:13])[C:2]([C@@H:4]([OH:12])[C@H:5]([OH:11])[C:6]([C:8]([OH:10])=[O:9])=[O:7])=[O:3].C(O)[C@H](O)[C@@H](O)[C@H](O)C(C(O)=O)=O>>[CH2:1]([OH:13])[C@@H:2]([OH:3])[C@@H:4]([OH:12])[C@H:5]([OH:11])[C:6]([C:8]([OH:10])=[O:9])=[O:7]

Participants

3

Reactant 2

HCID 1022872,5-diketo-D-gluconic acidHCID 1024242-keto-L-Gulonic acid

Product 1

HCID 30354562-keto-D-Gluconic acid

Procedure

The 2,5-diketo-D-gluconic acid produced by cultivating the strain (I) is directly converted into 2-keto-L-gulonic acid by the strain (II) without being isolated from the medium. The undesired 2-keto-D-gluconic acid produced by the strain (II) is converted into 2,5-diketo-D-gluconic acid by the strain (I) which is again converted into 2-keto-L-gulonic acid by the strain (II).

Workup

  1. customwithout being isolated from the medium

Sources & evidence

ORD record
ord-25780ebaf408406593cea63a90761699
Source dataset
uspto-grants-1987_09
Patent number
US04696897

Reaction notes

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