(4-(Morpholin-4-yl)phenyl)boronic acid → Tert-butyl 3-[[2-[(4-methylcyclohexyl)amino]-5-(4-morpholin-4-ylphenyl)pyrimidin-4-yl]oxymethyl]pyrrolidine-1-carboxylate
Reaction equation
[CH3:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[n:10][cH:11][c:12]([Br:29])[c:13]([O:15][CH2:16][CH:17]3[CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]3)[n:14]2)[CH2:6][CH2:7]1.[O:30]1[CH2:31][CH2:32][N:33]([c:36]2[cH:37][cH:38][c:39]([B:42]([OH:43])[OH:44])[cH:40][cH:41]2)[CH2:34][CH2:35]1>>[CH3:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[n:10][cH:11][c:12](-[c:39]3[cH:38][cH:37][c:36]([N:33]4[CH2:32][CH2:31][O:30][CH2:35][CH2:34]4)[cH:41][cH:40]3)[c:13]([O:15][CH2:16][CH:17]3[CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]3)[n:14]2)[CH2:6][CH2:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3eda6e97baa5405995c0190433b056f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)