Bicarbonate Ion → 6-[4-(3-bromopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Reaction equation

[Br:21][CH2:22][CH2:23][C:24](=[O:25])[Cl:26].[C:16](=[O:17])([OH:18])[O-:19].[Cl:27][CH2:28][Cl:29].[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:13][NH:12][C:11](=[O:14])[CH2:10][CH:9]2[CH3:15])[cH:6][cH:7]1.[Na+:20]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:13][NH:12][C:11](=[O:14])[CH2:10][CH:9]2[CH3:15])[cH:6][cH:7]1)[C:24]([CH2:23][CH2:22][Br:21])=[O:25]

Participants

Reactant 5

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 6344Dichloromethane

HCID 84944Propanoyl chloride, 3-bromo-

HCID 161928Ici 109,081

Product 1

HCID 140033506-[4-(3-bromopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Sources & evidence

ORD record: ord-837126d8158d4c3d90913290738706d7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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