2-(6-Bromopyridin-2-yl)-2-methylpropanamide → 2-{[6-(2-Amino-1,1-dimethyl-2-oxoethyl)pyridin-2-yl]amino}-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([C:8]([C:9](=[O:10])[NH2:11])([CH3:12])[CH3:13])[n:7]1.[NH2:14][c:15]1[s:16][c:17](-[c:23]2[c:24]([F:34])[cH:25][c:26]([C:30]([CH3:31])([CH3:32])[OH:33])[cH:27][c:28]2[F:29])[cH:18][c:19]1[C:20](=[O:21])[NH2:22]>>[c:2]1([NH:14][c:15]2[s:16][c:17](-[c:23]3[c:24]([F:34])[cH:25][c:26]([C:30]([CH3:31])([CH3:32])[OH:33])[cH:27][c:28]3[F:29])[cH:18][c:19]2[C:20](=[O:21])[NH2:22])[cH:3][cH:4][cH:5][c:6]([C:8]([C:9](=[O:10])[NH2:11])([CH3:12])[CH3:13])[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0cf3ed4511664c29b0dc6676320142f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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