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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2321Generated: October 23, 2026

5-Bromo-2-chloropyrimidine → 2-Chloro-5-(3-thienyl)pyrimidine

https://huagongshe.com/en/reaction/2321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
ReactantStannane, tributyl-3-thienyl-HCID 10959689—
Product2-Chloro-5-(3-thienyl)pyrimidineHCID 12356589—

Reaction Steps

2-Chloro-5-bromopyrimidine and 3-thienyltributyltin are treated in the same manner as in Example 190 to give 2-chloro-5-(3-thienyl)pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05728706
Source datasetuspto-grants-1998_03
ORD IDord-1e36bdd34f9c40229a1193bb06a3ce85
Source noteuspto-grants-1998_03