Acetone → 4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane

HRID 232187

Reaction equation

HRID 232187 reaction equation
[Br:1][CH2:2][CH:3]([OH:6])[CH2:4][OH:5].S([O-])([O-])(=O)=O.[Mg+2].[CH3:13][C:14]([CH3:16])=O>>[CH3:13][C:14]1([CH3:16])[O:6][CH:3]([CH2:2][Br:1])[CH2:4][O:5]1

Participants

4

Reactant 3

HCID 180AcetoneHCID 208273-Bromo-1,2-propanediolHCID 24083Sulfuric acid magnesium salt (1:1)

Product 1

HCID 1697594-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane

Procedure

An acetone solution of bromomethyl ethylene glycol is refluxed for 24 hours in the presence of anhydrous magnesium sulfate. The cooled reaction mixture is filtered and the solvent is removed to provide a residual crude product.

Workup

  1. customThe cooled reaction mixture
  2. filtrationis filtered
  3. customthe solvent is removed

Sources & evidence

ORD record
ord-137e2323cbb8440bab45f00bb57fe83c
Source dataset
uspto-grants-1989_07
Patent number
US04851502

Linked notes

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